Mei Hu Selected Research

Neuroinflammatory Diseases

1/2020	Zileuton ameliorates depressive-like behaviors, hippocampal neuroinflammation, apoptosis and synapse dysfunction in mice exposed to chronic mild stress.
12/2019	1-Methylnicotinamide attenuates lipopolysaccharide-induced cognitive deficits via targeting neuroinflammation and neuronal apoptosis.
10/2019	Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice.
7/2019	Protective effects of tauroursodeoxycholic acid on lipopolysaccharide-induced cognitive impairment and neurotoxicity in mice.
1/2019	Protective Effects of 1-Methylnicotinamide on Aβ1-42-Induced Cognitive Deficits, Neuroinflammation and Apoptosis in Mice.
10/2018	Neuroprotective effects of INT-777 against Aβ1-42-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice.
1/2018	Antidepressant-like effect of zileuton is accompanied by hippocampal neuroinflammation reduction and CREB/BDNF upregulation in lipopolysaccharide-challenged mice.
4/2017	Hippocampal CysLT1R knockdown or blockade represses LPS-induced depressive behaviors and neuroinflammatory response in mice.
2/2017	Preventive effect of genetic knockdown and pharmacological blockade of CysLT1R on lipopolysaccharide (LPS)-induced memory deficit and neurotoxicity in vivo.
1/2017	CysLT1R downregulation reverses intracerebroventricular streptozotocin-induced memory impairment via modulation of neuroinflammation in mice.

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Mei Hu Research Topics

Disease

22	Neoplasms (Cancer) 03/2024 - 10/2002
17	Neuroinflammatory Diseases 01/2020 - 02/2013
15	Cognitive Dysfunction 01/2022 - 08/2012
13	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 02/2013
10	Infections 07/2023 - 12/2003
8	Memory Disorders (Memory Loss) 02/2017 - 02/2013
6	Inflammation (Inflammations) 11/2023 - 04/2015
5	Shock 01/2023 - 04/2014
5	Neoplasm Metastasis (Metastasis) 05/2022 - 01/2018
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 09/2015
4	Hypertension (High Blood Pressure) 10/2022 - 01/2017
4	Asthma (Bronchial Asthma) 04/2015 - 04/2014
3	Closed Head Injuries 01/2022 - 03/2015
3	Fibrosis (Cirrhosis) 10/2021 - 12/2014
3	Hyperlipidemias (Hyperlipidemia) 01/2018 - 08/2012
3	Insulin Resistance 11/2017 - 08/2012
3	Hyperglycemia 01/2017 - 08/2012
2	Body Weight (Weight, Body) 12/2023 - 08/2012
2	Heart Failure 01/2023 - 01/2022
2	Obesity 01/2022 - 01/2017
2	Atherosclerosis 01/2022 - 11/2017
2	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2021 - 01/2020
2	Hypoxia (Hypoxemia) 01/2021 - 05/2017
2	Sarcoma (Soft Tissue Sarcoma) 01/2018 - 10/2002
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2017 - 01/2017
2	Chronic Traumatic Encephalopathy 03/2015 - 03/2015
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2014 - 04/2013
2	Brain Ischemia (Cerebral Ischemia) 12/2007 - 04/2007
2	Hepatitis E 03/2005 - 12/2003
1	Vascular Remodeling 11/2023
1	Bone Diseases (Bone Disease) 11/2023
1	Myocardial Infarction 08/2023
1	Wounds and Injuries (Trauma) 07/2023

Drug/Important Bio-Agent (IBA)

11	Amyloid (Amyloid Fibrils)IBA 08/2021 - 02/2013
8	Peptides (Polypeptides)IBA 01/2022 - 02/2013
7	CytokinesIBA 01/2022 - 04/2014
7	LipopolysaccharidesIBA 01/2020 - 02/2014
7	leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA 04/2017 - 04/2014
5	Proteins (Proteins, Gene)FDA Link 01/2023 - 12/2014
5	Caspase 3 (Caspase-3)IBA 08/2021 - 04/2014
5	Streptozocin (Streptozotocin)FDA Link 01/2017 - 08/2012
4	EnzymesIBA 01/2023 - 03/2015
4	Monoacylglycerol LipasesIBA 01/2023 - 03/2015
4	Neuroprotective AgentsIBA 01/2022 - 10/2018
3	DisintegrinsIBA 01/2023 - 01/2020
3	Paclitaxel (Taxol)FDA LinkGeneric 05/2022 - 01/2020
3	VaccinesIBA 01/2022 - 08/2012
3	glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA 01/2022 - 03/2015
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2022 - 08/2012
3	Biomarkers (Surrogate Marker)IBA 11/2021 - 01/2020
3	MicroRNAs (MicroRNA)IBA 04/2021 - 02/2014
3	Immunoglobulin M (IgM)IBA 01/2021 - 12/2003
3	Simvastatin (Zocor)FDA LinkGeneric 01/2020 - 01/2017
3	ProdrugsIBA 01/2018 - 07/2009
3	MicellesIBA 01/2018 - 11/2012
3	pranlukastIBA 01/2017 - 02/2013
3	montelukast (Singulair)FDA Link 12/2016 - 04/2014
2	Photosensitizing Agents (Photosensitizers)IBA 12/2023 - 12/2021
2	Peptide Hydrolases (Proteases)FDA Link 11/2023 - 01/2023
2	Adenosine Triphosphate (ATP)IBA 03/2023 - 01/2018
2	68Ga-pentixaforIBA 02/2023 - 12/2022
2	Metalloproteases (Metalloproteinases)IBA 01/2023 - 01/2020
2	Urea (Carbamide)FDA LinkGeneric 01/2023 - 01/2020
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	LigandsIBA 01/2022 - 01/2022
2	EndocannabinoidsIBA 01/2022 - 03/2015
2	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 11/2021
2	Angiotensin IIIBA 10/2021 - 01/2020
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 11/2019
2	Immune Checkpoint InhibitorsIBA 01/2021 - 12/2020
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2016
2	AntibodiesIBA 01/2021 - 03/2005
2	AntigensIBA 12/2020 - 02/2019
2	zileuton (Zyflo)FDA Link 01/2020 - 01/2018
2	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 01/2020 - 01/2018
2	N(1)-methylnicotinamideIBA 12/2019 - 01/2019
2	6alpha-ethyl-23(S)-methylcholic acidIBA 10/2019 - 10/2018
2	PolymersIBA 01/2018 - 06/2012
2	Nonesterified Fatty Acids (NEFA)IBA 11/2017 - 01/2016
2	oridoninIBA 05/2017 - 01/2017
2	LipidsIBA 01/2017 - 02/2013
2	Blood Glucose (Blood Sugar)IBA 01/2016 - 04/2013
2	Pioglitazone (Actos)FDA Link 04/2013 - 08/2012
2	Leukotriene D4IBA 02/2013 - 02/2013
2	Coloring Agents (Dyes)IBA 06/2009 - 04/2007
2	Immunoglobulin G (IgG)IBA 03/2005 - 12/2003
1	Choline (Choline Chloride)IBA 03/2024
1	azaBDPBA compoundIBA 12/2023
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 12/2023
1	Tissue Inhibitor of MetalloproteinasesIBA 11/2023
1	Guanidine (Guanidine Nitrate)FDA Link 08/2023
1	benzylguanidineIBA 08/2023
1	Nitrite Reductases (Nitrite Reductase)IBA 07/2023
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2023

Therapy/Procedure

8	Therapeutics 03/2023 - 02/2013
5	Immunotherapy 05/2022 - 01/2020
4	Drug Therapy (Chemotherapy) 01/2021 - 12/2014
2	Photochemotherapy (Photodynamic Therapy) 12/2023 - 12/2021
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 11/2023
1	Catheter Ablation 03/2023